RePORT China consortium joined RePORT International in January 2017 after signing the RePORT International Memorandum of Understanding and followed the bylaws, which set clear guidelines and expectations for current and future groups to work together on a broad set of common goals. China consortium developed a locally- tailored study protocol, manual of laboratory operations and case report forms (CRFs) for qualified cases enrollment, sample collection and storage, data collection and sharing based on the Common Protocol and biorepository standards by RePORT International. 7 sites (Beijing, Changsha, Fuzhou, Shanghai, Suzhou, Jingzhou and Zhenjiang) of RePORT China kept active contribution to the sample and data pool. 180 eligible participants set as the target for RePORT China has achieved with the actual number at 198 and samples originated from blood, urine and sputum were collected and stored with the total number at 12480. The 4th RePORT International Meeting was well organized by RePORT China in 2018. 2 projects were successfully funded by RePORT International Supplemental Funding RFP in 2019. “Dynamic detection of cytokines by liquid chip technology to evaluate the efficacy on anti-TB treatment” was hosted by RePORT China and cooperated with RePORT Philippines. The other one is “Pharmacokinetic assessment of MDR-TB drugs in the treatment of TB meningitis” led by Johns Hopkins University and RePORT China was on one of the sites.

FOCUS

The consortium aims to facilitate intra and inter consortium cooperation and research. Since 2019, the RePORT China consortium has co-operated with other RePORT consortia members to do cross-consortium research. 7 sites of RePORT China kept active contribution to the sample and data pool.180 eligible participants set as the target for RePORT China has achieved with the number of samples origin from blood, urine and sputum at 2446.

1

Jingzhou Chest Hospital

2

Fuzhou Pulmonary Hospital

3

Fifth People Hospital of Suzhou

4

Tianjin Haihe Hospital

5

Beijing Chest Hospital

6

Changsha Central Hospital

7

Third People’s Hospital of Zhenjiang

STUDIES

The topics of the two multi-consortium studies were “Dynamic detection of cytokines by liquid chip technology to evaluate the efficacy of anti-tuberculosis treatment” and “Pharmacokinetic Assessment of MDR-TB Drugs in the Treatment of TB Meningitis” respectively supported by CRDF Global.

Liu Yuhong

Liu Yuhong

CCTB

National Clinical Centre on Tuberculosis, China CDC
Beijing Chest Hospital

Jingtao Gao

Jingtao Gao

CCTB

National Clinical Centre on Tuberculosis, China CDC
Beijing Chest Hospital

Qian Gao

Qian Gao

CCTB

School of Basic Medical Sciences, Fudan University

funding

RePORT China was funded locally by the Innovation Alliance on TB Diagnosis and Treatment (Beijing) for about $ 94,000.